Pioglitazone is the single ingredient in Actos. When combined with metformin (another diabetes medication), it is sold as Actoplus Met and Actoplus Met XR (extended release). Pioglitazone combined with the diabetes medication glimepiride is sold as Duetact.
Actos plus a proper diet and exercise are meant to improve control of blood sugar in adults with type 2 diabetes mellitus. According to the FDA, more than 2 million people filled prescriptions for Actos in 2010.
However, in June 2011, the U.S. Food and Drug Administration said that taking pioglitazone-containing medications such as Actos for more than one year may be associated with an increased risk of bladder cancer.
If you or a loved one of yours took Actos and developed bladder cancer, contact Salvi, Schostok & Pritchard P.C. today at our toll-free number or through our online form . We are investigating legal claims related to Actos and bladder cancer, and we may be able to help you. Drug injury claims involve complex legal issues, so it is important to act quickly.
Investigation into Actos and the Risk of Bladder Cancer
Actos is manufactured by Takeda Pharmaceuticals of Japan and is marketed in the U.S. by Eli Lilly & Co. Since pioglitazone, the single active ingredient in Actos, was first approved by the FDA in 1999, doctors have prescribed Actos to millions of diabetes patients.
In its June 2011 warning, the FDA said patients who had used pioglitazone for longer than 12 months showed a 40 percent increase in the risk of developing bladder cancer.
Data from the French National Health Insurance Plan covering about 1.5 million diabetes patients followed for up to four years also showed a statistically significant increase in the risk for bladder cancer in patients using pioglitazone compared to patients taking other diabetes medications, the FDA said.
Signs of bladder cancer include:
- Bloody or reddish urine
- Frequent urination
- An urgent need to urinate
- Urine leakage (incontinence)
- Pain during urination
- Pain in the back or lower abdomen.
If you have any of these symptoms, you should immediately seek medical attention.
Legal Options for Actos Users
If you or a loved one of yours has developed bladder cancer after taking Actos or another pioglitazone-containing diabetes medication, you may have the legal right to hold the manufacturer and distributor of the drug accountable for the harm you have endured.
The lawyers of Salvi, Schostok & Pritchard P.C. are investigating cases of injuries and death that may be attributable to Actos. We can advise you about the legal options available to you if you believe Actos has played a role in your or a loved one’s bladder cancer.
Since our firm was founded, we have obtained more than $800 million for our clients, including in excess of 198 multimillion-dollar verdicts and settlements. We can put our experience to work for you, too.
To schedule a free, no-obligation consultation, call us today toll-free or take a moment to fill out our online form.